Soft tissue sarcoma in adolescent and young adult patients: a retrospective study using a nationwide bone and soft tissue tumor registry in Japan

Abstract Objective The relationship between the adolescent and young adult age groups poor overall survival in soft tissue sarcoma risk factors for outcomes patients with were analyzed. Methods medical records of 7759 Japanese diagnosed from 2006–13 accessed Bone Soft Tissue Tumor registry. epidemiological features compared those other groups. cancer rates calculated using Kaplan-Meier method. prognostic analyzed Cox proportional hazards models. primary endpoint prognosis was tumor-related death. Results There 210 children, 1467 adults, 2771 adults 3311 elderly among identified sarcoma. Compared groups, proportions myxoid/round cell liposarcoma, synovial sarcoma, malignant peripheral nerve sheath tumor, primitive neuroectodermal tumor rhabdomyosarcoma highest, but none significantly more prevalent patients. On multivariate analysis, not a factor poorer than groups; however, on analysis Conclusions Our study is first to investigate nationwide Adolescent Japan.